About this podcast

Dive into the cutting-edge science of aging and longevity with Dr. David Sinclair, a leading expert and professor of genetics at Harvard Medical School. In this Huberman Lab Essentials episode, Dr. Sinclair discusses the fundamental cellular and molecular mechanisms that drive aging, challenging the traditional view by framing aging as a disease. The conversation explores how specific lifestyle choices, such as strategic fasting, regular exercise, and the use of NAD+-boosting compounds like NMN, can actively engage the body's natural longevity pathways. Discover how the epigenome plays a crucial role in controlling gene expression and how understanding this 'information loss' model of aging can lead to actionable protocols for slowing down and potentially reversing key aspects of biological aging. This episode provides essential science and practical takeaways that profoundly illustrate how our daily habits influence our lifespan and healthspan.