About this podcast

In this compelling episode, Dr. David Fajgenbaum, a professor of translational medicine and human genetics at the University of Pennsylvania, joins Andrew Huberman to share his extraordinary journey of discovering life-saving treatments for his own rare Castleman's disease by repurposing existing drugs. The conversation delves into the often-overlooked potential of approved medications to treat or cure conditions far beyond their original intended uses. Dr. Fajgenbaum, also the founder of Every Cure, highlights how researchers, physicians, and the general public can actively explore novel treatments, even for diseases deemed untreatable, including various cancers. The discussion also emphasizes the critical role of mindset in battling illness and explores lesser-known compounds for health and longevity. This episode is a call to action for greater patient agency and a deeper understanding of the vast, untapped potential within our current pharmaceutical arsenal.