In this insightful episode, Dr. Andrew Huberman hosts Dr. Gabrielle Lyon, a board-certified physician and leading expert in geriatrics and nutrition. They delve into the critical role of healthy skeletal muscle in promoting longevity, enhancing brain health, preventing disease, and optimizing overall body composition and organ function. Dr. Lyon provides evidence-based protocols for nutrition, including specific recommendations on what, how much, and when to eat, emphasizing the essential need for quality protein across all ages. The discussion also covers the importance of targeted resistance training for building and maintaining muscle, regardless of age or sex. Listeners will gain practical, science-based tools for improving physical appearance, function, and long-term health, complemented by mindset strategies for sustained adherence to healthy practices.