About this podcast

Dive deep into the fascinating world of pain and pleasure with neurobiologist Andrew Huberman. This insightful episode explores the intricate neural circuits in our mind and body that give rise to these fundamental sensations, and critically, how we can learn to control their intensity. Dr. Huberman discusses the science behind behavioral tools like acupuncture, hypnosis, and directed pressure, revealing how they modulate our experience of pain or pleasure. Discover the surprising link between visual perception and pain modulation, the plasticity of our pain system, and novel compounds for pain relief such as Acetyl-L-Carnitine and Agmatine. The episode also unravels the complex interplay between dopamine, serotonin, and oxytocin with arousal, pleasure, and particularly motivation. Learn actionable, science-based protocols to experience more pleasure and less pain in your daily life.