About this podcast

In this compelling episode, host Andrew Huberman welcomes Dr. Robert Lustig, a renowned neuroendocrinologist and professor of pediatrics at UCSF, to dissect the profound effects of sugar and processed foods on our health. The discussion challenges the conventional 'calories in - calories out' model, diving deep into how specific macronutrients, fiber, and various forms of sugar—especially fructose—influence insulin levels, liver function, kidney health, and metabolic processes. Listeners will gain critical insights into how non-fruit fructose sources can be addictive, mimicking drugs of abuse by altering brain circuits related to cravings and satisfaction. The episode also explores sugar's role in childhood and adult obesity, its impact on gut and mental health, and the food industry's strategic use of refined sugars to create 'pseudo foods.' Packed with actionable information, this conversation is essential for anyone seeking a thorough understanding of how dietary choices shape immediate and long-term well-being.